Leukaemic Niche and redOx metabolism (LNOx)

Head : Pr. Olivier HERAULT

LNOx team is focused on the characterisation of oxidative stress (free radicals, antioxidative enzymes, etc.) in the pre-leukaemic states (myelodysplasia) and leukaemia in relation to the bone marrow microenvironment and more particularly within the leukaemic niche. This fundamental research opens up new therapeutic perspectives, focused on the pharmaco-modulation of oxidative stress and interactions between leukaemia cells and their microenvironment, in order to increase their chemosensitivity.
Team 2 is involved in the MicroNIT network
Olivier Hérault  (University Professor & Hospital Practitioner)

CNRS Senior scientist
Fabrice Gouilleux

Inserm Senior scientist
Frédéric Mazurier

University Professor & Hospital Practitioner
Emmanuel Gyan

Florence Bonnin-Rouleux

Assistant clinic leader
Julien Lejeune