Leukaemic Niche and redOx metabolism (LNOx)

LNOx team is focused on the characterisation of oxidative stress (free radicals, antioxidative enzymes, etc.) in the pre-leukaemic states (myelodysplasia) and leukaemia in relation to the bone marrow microenvironment and more particularly within the leukaemic niche. This fundamental research opens up new therapeutic perspectives, focused on the pharmaco-modulation of oxidative stress and interactions between leukaemia cells and their microenvironment, in order to increase their chemosensitivity.
 

• Collaborations
• Publications

Team 2 is involved in the MicroNIT network
www.micronit.fr

Head
Olivier Hérault  (University Professor & Hospital Practitioner)

CNRS Senior scientist
Fabrice Gouilleux

Inserm Senior scientist
Frédéric Mazurier

University Professor & Hospital Practitioner
Emmanuel Gyan

Lecturer
Florence Bonnin-Rouleux

Assistant clinic leader
Julien Lejeune

Post-doc
Marie Brachet

Engineers and technicians
Jérôme Bourgeais
Laetitia Corset-Babin
Elfi Ducrocq
Sophie Hamard
Georges Khamis
Nathalie Langonne
Emmanuel Pecnard
Frédéric Picou

PhD students
Amélie Foucault
Noémie Ravalet